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| Microsocopy Laboratory (Cornelia Hall Room GR12) | ||
Our research laboratory is located in Cornelia Hall Room GR12.
A technique that is central to our research is the inverted digital video microscopy with the micropipet manipulation technique, also referred to as micromanipulation. Our system is composed of 1) an experimental station (an inverted microscope with a micromanipulator); 2) data acquisition station (a digital camera/PC interface); 3) distribution system (digital library, images and videos); and 4) display (projection system) as shown below. The progress of the reactions is visualized and recorded in real-time. Using a computer interface, still images and/or video clips (AVI, MPEG) can be easily recorded and edited to appropriate video media for future use and distribution. By connecting the computer to a projection system, an entire class can observe the dynamics of reactions from a single camera on a microscope.
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Inverted Digital Video Microscope with Micropipet Manipulation
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This technique has been originally developed and used to measure the mechanical properties of the cell membrane, now extending to lipid bilayer vesicles, liposomes, gaseous microbubbles, and liquid emulsion droplets. |
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Micropipet technique allows the experimenter directly manipulate individual and pairs of particles at the micron-scale. This method offers a versatile and unique method for studying single droplet chemistry and droplet-droplet interactions that occur in micron-sized particles. |
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With a micropipette technique, we have a better insight into the materials properties and behavior of such microparticulate systems, and eventually have a deeper understanding of how composition, relates to structure, property and performance. |
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Micropipet Puller and Microforge
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Micropipet with the desired diameter is made by a micropipet puller (left) and refined further using a microforge (right). Typical pipet diameter for our study is in the range of 5 - 20 micrometer. |